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Labial minor salivary gland biopsy in the diagnosis of Sjögren syndrome — own experience

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Katarzyna Błochowiak, Marzena Wyganowska‑Świątkowska



2/2018/XLVI s. 145–149
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DOI: https://doi.org/10.20883/df.2018.19

Fraza do cytowania: Błochowiak K., Wyganowska‑Świątkowska M. Labial minor salivary gland biopsy in the diagnosis of Sjögren syndrome — own experience. Dental Forum. 2018;XLVI(2):145–149. DOI: https://doi.org/10.20883/df.2018.19.

Introduction. Labial minor salivary gland biopsy is applied for the diagnosis of Sjögren syndrome (SS). The microscopic confirmation of SS is based on the presence of focal lymphocytic sialadenitis (FLS) with a focus score ≥ 1 per 4 mm2 of glandular tissue. Aim. The aim of this study was to present the authors' experience and recommendations on taking labial salivary gland biopsies with respect to their histologic criteria, surgical technique, complications, and their usefulness for diagnostic procedures. Conclusions. The most recommended site is the normal looking mucosa of the lower lip. The recommended technique is a 1.0 to 1.5 cm linear, horizontal incision of the mucosa parallel to the vermillion border and lateral to the midline with the tip of a 15 scalpel or a 1 cm lenticular excisional biopsy of the mucosa. The tissue specimens should include only salivary glands with a minimum number of 2–3 glands and without muscular or other tissues. The possible complications of biopsy are lip numbness, pain, swelling or mucocele.

Key words: Sjögren syndrome, labial salivary gland, biopsy.





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