Introduction. The mouthwash Dentofresh® produced by Phytopharm Kleka SA, intended for adults and children over the age of 6, is a prophylactic preparation. Using the mouthwash after having brushed the teeth has a preventive and healing influence on the hard tissues of teeth and gingiva. The mouthwash contains: eucalyptus, mint, thyme and sage oils, which show anti‑inflammatory and antimicrobial activity. Aim. The aim of the study was to evaluate the effectiveness of Dentofresh® against strains of yeast‑like fungi from the genus Candida. Material and methods. The study was conducted on 15 strains of yeast‑like fungi from the genus Candida isolated from infections, and five reference strains. The fungicidal activity of the preparation (MFC – Minimal Fungicidal Concentration) against the strains of yeast‑like fungi at the concentration recommended by its producer was evaluated. Results. Dentofresh® exhibited great fungicidal activity at the concentration recommended by the producer as quickly as 15 minutes after it was applied (against 87% of the strains), while after 30 minutes, all the tested strains of yeast‑like fungi were destroyed. Conclusions. The preparation was effective against the genera of yeast‑like fungi which are usually resistant to common antifungal medicines.

Key words: Candida sp., essential oils, Dentofresh®.